Board your river ship for your Flavors of Portugal & Spain cruise. (D)

Join a guided tour of Porto’s historic quarter, a UNESCO World Heritage Site. You’ll see the Cathedral, one of the city’s oldest monuments; the main square, ringed with shops and cafes; and the São Bento Railway Station, known for its blue and white tile panels depicting scenes from Portuguese history. You’ll also enjoy a tasting of port, Portugal’s most renowned contribution to the world of wine. For the more active adventure, join a hike in Porto and explore the old harbor quarter, passing through the medieval streets of Porto. In the afternoon, visit Guimarães, the “birthplace of the Portuguese nationality,” on a very special excursion. Continue to Quinta de Sezim where you’ll enjoy a visit to the baron’s winery for a wine tasting on the terrace. (B,L,D)

Entre-os-Rios translates to “between the rivers,” and this small village is, quite appropriately, located at the confluence of the Tâmega and Douro rivers. For an authentic slice of Douro River life, enjoy a traditional “home-cooked” meal at a local quinta. (B,L,D)

Begin your day with a tour of the 18th-century Palacio Anadia, or Palace of the Counts, known for its beautiful interior and Baroque style. Inside the house, you’ll see intricate panels of blue and white tiles throughout the rooms and a striking vaulted ceiling that retell the history behind the palace. (B,L,D)

Venture to the town of Lamego, where you’ll see the “Sanctuary of Our Lady of Remedies” on a city tour or climb the 686-step “Holy Staircase,” beautifully decorated with white and blue tiles, to the top on a guided hike. Whichever excursion you choose will conclude with a tasting of local specialties such as Bôlas de Lamego, bread filled with smoked ham; Presunto, a type of dry-cured ham; and Espumante, a Portuguese sparkling wine. Later in the day, cruise along the scenic Douro to Pinhão, where a wine tasting will be waiting for you in a local quinta. (B,L,D)

Embark on a leisurely walk to the charming Pinhão Railway Station, a stunning train station along the Douro Line, one of the most iconic rail journeys in Portugal. The station’s main building is revered for its 25 tile panels, all in shades of blue, that depict scenes from the Douro region. Afterward, enjoy an exclusive lunch at Quinta da Avessada, where you’ll enjoy an authentic and traditional dining experience complete with entertainment. The warm, spirited hospitality of this family-run quinta is quite special as you will discover. Several family members play in a band, and while dining, they will entertain you. Quinta de Avessada is also a fascinating interactive museum commemorating the history and culture of wine in the Alto Douro region, so you’ll have fun discovering all the various stages of wine production as well as doing plenty of tasting. Later in the day, indulge in some free time to explore the town on your own. (B,L,D)

Venture to Castelo Rodrigo, known as the “White Village” because of its almond trees. The site offers spectacular views of the surrounding area and as far away as Spain. Join a walking tour through its medieval streets and see the houses and establishments with 16th-century facades and Manueline style windows. Prefer a more active adventure there, you can hike to the town. At the end of both tours, enjoy a tasting of local favorites, such as almonds, cheese, bread and wine. (B,L,D)

Your journey comes to an end in Vega de Terrón as you prepare for your homeward flight. (B)

Arrive in Lisbon and check in to your hotel.

One of Europe’s most beautiful cities, Lisbon stretches across several hills along the Tagus River. On your escorted tour, you’ll see Belem Tower, a fortified four-story tower made of limestone, and visit the Late Gothic Jerónimos Monastery, the burial place of many Portuguese kings and heroes. You will also taste a typical Portuguese pastry, Pastéis de Belém, before going to Discoveries Monument, built in honor of Portugal’s greatest maritime explorers. (B)

Enjoy a morning excursion to Serra de Sintra, one of the most picturesque mountain villages in Portugal, a former summer residence of the Portuguese royal family and a source of inspiration for Lord Byron and generations of other artists and poets. Your guided tour includes a wine tasting and a view of the Pena National Palace, a fairy tale castle situated high on a rocky peak, followed by free time to explore on your own. (B)

Check out of your hotel and take a motorcoach ride through the Portuguese countryside. Stop in Tomar and visit the castle of the Knights Templar, the walls of which envelop the elaborate Convent of Christ, a UNESCO World Heritage Site from the 12th century boasting spectacular frescoes and azulejos (iconic blue painted tiles). Afterward, continue to Porto where you'll board your ship. (B,D)

Join a guided tour of Porto’s historic quarter, a UNESCO World Heritage Site. You’ll see the Cathedral, one of the city’s oldest monuments; the main square, ringed with shops and cafes; and the São Bento Railway Station, known for its blue and white tile panels depicting scenes from Portuguese history. You’ll also enjoy a tasting of port, Portugal’s most renowned contribution to the world of wine. For the more active adventure, join a hike in Porto and explore the old harbor quarter, passing through the medieval streets of Porto. In the afternoon, visit Guimarães, the “birthplace of the Portuguese nationality,” on a very special excursion. Continue to Quinta de Sezim where you’ll enjoy a visit to the baron’s winery for a wine tasting on the terrace. (B,L,D)

Entre-os-Rios translates to “between the rivers,” and this small village is, quite appropriately, located at the confluence of the Tâmega and Douro rivers. For an authentic slice of Douro River life, enjoy a traditional “home-cooked” meal at a local quinta. (B,L,D)

Begin your day with a tour of the 18th-century Palacio Anadia, or Palace of the Counts, known for its beautiful interior and Baroque style. Inside the house, you’ll see intricate panels of blue and white tiles throughout the rooms and a striking vaulted ceiling that retell the history behind the palace. (B,L,D)

Venture to the town of Lamego, where you’ll see the “Sanctuary of Our Lady of Remedies” on a city tour or climb the 686-step “Holy Staircase,” beautifully decorated with white and blue tiles, to the top on a guided hike. Whichever excursion you choose will conclude with a tasting of local specialties such as Bôlas de Lamego, bread filled with smoked ham; Presunto, a type of dry-cured ham; and Espumante, a Portuguese sparkling wine. Later in the day, cruise along the scenic Douro to Pinhão, where a wine tasting will be waiting for you in a local quinta. (B,L,D)

Embark on a leisurely walk to the charming Pinhão Railway Station, a stunning train station along the Douro Line, one of the most iconic rail journeys in Portugal. The station’s main building is revered for its 25 tile panels, all in shades of blue, that depict scenes from the Douro region. Afterward, enjoy an exclusive lunch at Quinta da Avessada, where you’ll enjoy an authentic and traditional dining experience complete with entertainment. The warm, spirited hospitality of this family-run quinta is quite special as you will discover. Several family members play in a band, and while dining, they will entertain you. Quinta de Avessada is also a fascinating interactive museum commemorating the history and culture of wine in the Alto Douro region, so you’ll have fun discovering all the various stages of wine production as well as doing plenty of tasting. Later in the day, indulge in some free time to explore the town on your own. (B,L,D)

Venture to Castelo Rodrigo, known as the “White Village” because of its almond trees. The site offers spectacular views of the surrounding area and as far away as Spain. Join a walking tour through its medieval streets and see the houses and establishments with 16th-century facades and Manueline style windows. Prefer a more active adventure there, you can hike to the town. At the end of both tours, enjoy a tasting of local favorites, such as almonds, cheese, bread and wine. (B,L,D)

Disembark the ship in Vega Terrón and board a motorcoach to Madrid. En route to Madrid, you’ll first stop in Salamanca, a UNESCO World Heritage Site located at the center of Spain’s Castilla y León region. You will have free time to explore on your own, followed by an escorted city tour that includes the New Cathedral and the uniquely adorned House of Shells. Later in the day, you’ll check into your hotel in Madrid. (B)

Discover the vibrant capital of Spain on your city tour that takes in all the top sights, including the elaborate Royal Palace, Buen Retiro Park, Puerto del Sol, Mercado de San Miguel and Plaza Mayor. (B)

Journey to the walled city of Toledo, a UNESCO World Heritage Site and the ancient capital of Spain. The city is a treasure trove of artistic riches with its winding streets and well-preserved medieval architecture. As part of your escorted tour, you will visit the Cathedral of Toledo as well as the Synagogue Santa María La Blanca in the Jewish Quarter. (B)

Check out of your hotel for your flight home. (B)